In the Southern Province of Rwanda up to date techniques of sustainable agriculture are not implemented due to a lack of knowledge by farmers. The current production techniques don’t guarantee sufficient food and feed production and result in a decline of the soil fertility. By strengthening the capacity of the University of Rwanda (CAVM = College of Agriculture, Animal Sciences and Veterinary Medicine) and through a strong local partnership, an integrated sustainable agriculture model will be developed and implemented in 4 districts on 4 selected demonstration sites. It takes into account the identified 3 priorities of the local NGO’s to be tackled in their transformation towards a more sustainable agricultural model: (1) Availability and quality of seeds (in particular maize, soybean and disease-resistant varieties of cassava); (2) Soil fertility with emphasis on an analysis-based approach, rational rotations, legumes, fodder trees and prevention of erosion; (3) Feeding of dairy cows with newly introduced methods of forage production and conservation. This will contribute to food security for the beneficiary farmers.