Dietary exposure to multi-mycotoxins as a predisposing factor for oesophageal squamous cell carcinoma in Malawi

Date
October 2019 to September 2023
Countries
Members
Keywords
oesophageal squamous cell carcinoma (ESCC)
mycotoxins
fumonisins
epidemiology
risk assessment
Research fields
Agriculture and Food Sciences
Medicine and Health Sciences

Malawi has the highest age-standardized rate of oesophageal carcinoma (ESCC), and relies on maize as staple food. Common mycotoxins in maize - fumonisins and aflatoxins- have been linked with an increased risk of ESCC in areas of intensive maize farming. This study aims at measuring the extent of mycotoxins in maize, and establishing associations between exposure and risk of ESCC-development.